Has your health system prepared for HRSA’s forthcoming 340B Rebate Model Pilot Program, scheduled to begin January 1, 2026? We have. At the bottom of this post, you’ll find a detailed overview of exactly how our 340B team has prepared to help the 340B health systems we serve — including a short-term loan program we’ll … Read More
What Does The Future Hold For 340B, And How Can You Prepare?
Since 2019, VytlOne has supported the 340B programs of more than 100 health systems and health centers. We’ve published dozens of posts exploring 340B topics and trends — major, minor and developing. Recently, we were asked by a reader to produce a post offering our thoughts on, and predictions for, the program’s future. If there … Read More
Bausch Has Pulled Its Drug Catalog From The 340B Program.
How can this unprecedented manufacturer restriction generate the company, OR patients, a net benefit? It would not be an exaggeration to say that Bausch Health (BHC) sent shockwaves through much of the healthcare industry in declaring its intention to cease participation in what it deemed two “optional” Federal drug pricing programs — the Medicaid Drug … Read More
The Holistic Pharmacy Approach To 340B Patient Support
How to make Pharmacy “The Easy Part” of the patient experience. Anyone who’s ever been a hospital patient, or patient caregiver, knows that the mental strain of a serious illness can often match the negative impact of the physical trauma. Particularly when an illness is chronic and/or long-term, the stress involved in managing the details … Read More
Optimize 340B Program Savings & Compliance With Data Mining
Since late 2019, VytlOne has supported the 340B programs of 33 health systems and 38 health centers. Altogether, we’ve generated nearly $1 billion in pharmacy-related savings for our clients. We analyze 340B program-savings potential for dozens of prospective clients every year. And not once have we ever served, or encountered, a health system capable of … Read More
The Definitive 340B Compliance Checklist For 2025
Download Our Free Compliance Checklist PDF 340B health systems have been under increasing scrutiny and regulatory oversight in recent years. The Health Resources and Services Administration (HRSA) has indicated that it plans to increase the number and complexity of 340B program audits it conducts. Here’s how your health system can prepare every aspect of … Read More
Why A 340B Hospital Should Own A Specialty Pharmacy. Why Not.
Before we begin, we’re going to be honest with you. A significant component of VytlOne’s business is guiding 340B health systems through the process of building, accrediting, funding, launching and managing on-campus specialty pharmacies. Many times in this space, we’ve maintained that every 340B hospital should consider owning a specialty pharmacy. We’re currently in the … Read More
So You Want To Build A 340B Specialty Pharmacy. How Hard Can It Be?
Fair Warning: If you ever dismissively ask that question (above) of someone who’s led the planning and launch of a 340B hospital’s specialty pharmacy, and did it with no outside support, there’s a good chance you’ll get punched. Yes, it’s that difficult. POST OUTLINE Why is it so hard to build a 340B specialty … Read More
How Recent 340B Changes Impact Specialty Pharmacies In 2025
The evolving legal and legislative landscape surrounding the 340B Drug Pricing Program has significant implications for hospitals’ specialty pharmacies. Here’s a breakdown of the new developments and their likely impacts: Recent 340B changes and their impact on specialty pharmacies 1. 340B contract pharmacy restrictions Drug manufacturers have increasingly restricted the use of contract pharmacies, especially … Read More
How To Use Your 340B Program As a Community Health Engine
We all know the 340B Drug Pricing Program was designed to enable eligible healthcare organizations to stretch scarce federal resources in serving underserved patients and expanding their missions in the community services. What we at VytlOne have learned in supporting the 340B programs of more than 100 health systems and health centers is that, properly … Read More










